Cell free DNA as a biomarker in medicolegal assessment in burn patients

Background: Burn victims have higher levels of cell free DNA (cfDNA), which allows its use as a direct indicator cellular damage and burn vitality. Aim: Determination cfDNA in patients their correlation with total body surface area burned percent (TBSA%). Subjects methods: cases were evaluated to determine the prevalence age sex variations, period admission, TBSA%, etiology manner burns. The plasma concentration was measured within 24 hours injury 40 20 control subjects. Results: mean 34.38 years (median 33 years). Most males (62.5%). Burning by flame or scalding represented 50% cases. Accidental burns most predominant. admission periods 36.55 days while value TBSA% 16.68%. There statistically significant difference values between subjects (p = 0.001). A positive found (r 0.7; p < Conclusion recommendations: Levels significantly different controls.